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The Role of Rhes Protein in the Dopaminergic System of Rodents
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Rhes is a new protein that is highly expressed in the§striatal system of rodents. In the present book, it§is described experimental work about the role of this§protein in behaviors mediated by the striatal§dopaminergic system. Some of the behavioral§paradigms described are stereotypy, anxiety and basal§levels of activity. The mutant mice model used is§the rhes ko mice. Female groups are included for all§the experiments. Very interesting gender differences§are found in anxiety and stereotypy. The present§work give evidence of the role of rhes protein in§dopamine receptor supersensitivity; this is relevant§for conditions like schizophrenia, Parkinson disease,§ADHD and others. This book represents one of the few§works that have been performed in the role of rhes§protein in behavioral neuroscience.
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