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Protective role of Hesperidin & Allopurinol against Gamma radiation
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There are many types of radiation damage to normal tissues. The types of damage depend on the cells and organs being irradiated, the dose and dose rate of the exposure, and the time after exposure that is being assayed for a radiation effect. Many of the types of damage seen after irradiation can be ameliorated by antioxidants. Generally speaking, we can increase the amount of antioxidants in our diet by consuming what we all know is good for us: fresh, organic fruits and veggies (especially those with brighter and more vibrant color), certain herbs and spices, and certain supplements that research has shown can protect us from radiation damage. Hesperidin showed antioxidant and anti-apoptotic activities. It has a protective role against oxidative stress, injury and apoptosis induced by Gamma-radiation in testes. Protection is more effective when hesperidin is given before rather than after exposure.
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