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Pancreatic Islet Biology comprehensively discusses the development, in the laboratory, of insulin-producing cells. This is the topic of greatest focus and most interest to stem cell biologists engaged in finding a cure for diabetes. It encompasses multiple aspects of islet biology- from embryonic development and stem cell differentiation to clinical studies in islet transplantation and coverage of relevant topics like regulation of beta cell regeneration, pancreatic progenitors, mathematical modeling of islet development, epigenetic regulation, and much more. The chapter authors represent laboratories around the world and contribute international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicin e series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.