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This issue of "Nursing Clinics", Guest Edited by Margaret Mahon, PhD, RN, FAAN, on the topic of Palliative and End of Life Care will include the following article topics: 'I Want to Live Until I Don't Want to Live Anymore': Understanding Children's Involvement in Medical Decision Making; Symptom Management at the End of Life; Assessing Respiratory Distress when the Patient Cannot Self Report; Legislative Issues in Palliative Care; Barriers to Palliative Care; Saving Lives as Role in Palliative Care; End Stage Liver Disease: Symptoms and Practice Implications; Dying Children; Decision Making in Palliative Care; Children and Family Perspectives; Cognitive Impairments in Long Term Care; Withdrawal of Life and Sustaining Therapy - Good Death, Bad Death; Living with Cancer; and, Palliative Concepts in the Sickle Cell Population.