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This volume focuses on the structural biology of cytochrome-c oxidase - the enzyme most fundamental to aerobic life -, and on the physiology of oxygen homeostasis. It consists of five sections: cytochrome oxidases; cytochrome P-450 monooxygenase; various types of oxidases and oxygenases; oxygen sensing and regulation of blood flow; pathology and physiology of gaseous monoxides. Together, they describe oxygen homeostasis and its dynamics, and its vital importance in biology and medicine today. An invaluable resource and reference for clinicians and researchers in the medical sciences and biochemistry.