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This book brings together in one volume a large amount of information on the progress that is being made in developing novel and improved methods of cancer treatment. The first part of the book reviews areas such as: - physical treatment, including radiation therapy and hyperthermia; - chemotherapy, with particular interest in new drugs and methods of overcoming drug resistance; - biological approaches, including biological response modifiers, monoclonal antibodies and hormonal therapies; - and future approaches, such as the prevention of metastases, the induction of differentiation or even the utilization of the specific molecular lesions in cancer as a target for therapy. The second part deals with recent progress and future directions in particular types of cancer. The book is well referenced so as to serve as a base for more detailed exploration of any given topic. The dissemination of such new information aims to foster additional collaborative studies and possibly the development of new research protocols.