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This book constitutes the thoroughly refereed post-proceedings of the International Workshop on Membrane Computing, WMC-CdeA 2002, held in Curtea de Arges, Romania, in August 2002.§The 29 revised full papers presented were carefully selected during two rounds of reviewing and revision; some were especially solicited for inclusion in the book after the workshop. Most papers address membrane systems and membrane computing from the point of view of theoretical computer science; some papers solve open problems and present new approaches, and others provide mathematical and biological background. All in all, the book presents the state of the art in membrane computing.