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This§volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts§ranging from human cancers to cardiovascular disease and ageing. The role of§lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past§retroelements integrated within the human genome, as well as the role these§pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further,§the book examines the function of lncRNAs in diseases such as diabetes, in smooth§muscle formation, and in the modulation of nuclear receptors, as well as in§connection with perspectives§on the development of§personalized therapeutics. It offers an appealing and insightful resource for§scientists and clinicians alike.§