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Hydrolysis of whey proteins in enzymatic membrane§reactors is a promising technology. Dr Cheison§provides a compulsive read in this monograph which§covers experimental design and optimisation of§experiments. Apart from immense savings on the enzyme§as well as the favourable conditions for optimal§enzyme kinetics due to the continuous removal of the§nuisance of product inhibitors, enzymatic membrane§reactor technology in is dogged by a setback in rapid§flux declines and lower productivity.§§The influence of the hydrolysis mixture§temperature, the hydrodynamic properties like§recirculation speed and the influence of the enzyme§of membrane co-detergence are covered in a manner not§covered before. This monograph calls the research§community to revisit the set-backs of membrane flux§declines by optimising the role of the enzyme and§hydrodynamics in membrane cleaning.