HEMATOPATHOLOGY BOARD REVIEW HANDBOOK

The bone marrow biopsy is on your desk, the flow cytometry panel just resulted, and the differential still spans three WHO categories. Can you walk through the immunophenotype, name the defining genetic lesion, and commit to an answer before the tumor board meets?

Hematopathology sits at the intersection of morphology, flow cytometry, cytogenetics, and molecular genetics, and board exams test all four at once. Trainees are expected to recognize a ring sideroblast, read a CD10/CD5/CD23 panel, and place an entity correctly within the current WHO or ICC framework, often from a single vignette with no second chance to ask for more stain.

Hematopathology Board Review Handbook closes that gap with 25 chapters built around the actual rhythm of sign-out and exam day. Each chapter combines:

• Rapid Review boxes that distill each entity to a 5-to-6-word scannable recall cue
• Drug Dosing Snapshot tables for the chemotherapy and targeted-agent regimens boards expect you to know
• Red Flag alerts marking findings that change management immediately
• Case vignettes with full diagnostic reasoning, not just a final answer

Coverage spans normal marrow architecture, flow cytometry principles, myelodysplastic syndromes, acute myeloid and lymphoblastic leukemias, the myeloproliferative neoplasms, chronic lymphocytic leukemia, the full spectrum of B-cell and T-cell lymphomas, plasma cell neoplasms, Hodgkin lymphoma, and histiocytic disorders, anchored throughout to WHO, ICC, NCCN, and International Myeloma Working Group criteria.

This 2026 edition includes more than 50 clinical illustrations with precisely labeled morphology, flow plots, and cytogenetic findings, built to reinforce exactly what boards test. A QR code inside links to a companion video course of over 100 curated lectures organized by chapter, so review continues past the page.

Whether preparing for hematopathology boards or sharpening bench-side diagnostic confidence, this reference is built to be opened at the microscope, not just before the exam.