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The first observations on heat shock proteins and the heart were made in the 1980s, and interest in these proteins has increased over the decade. In the last few years there has been an exponential growth in the number of papers published on heat shock proteins and the heart. Heat shock proteins have been implicated in a number of cardiovascular research areas including ischemia, hypertrophy, aging, and atherosclerosis, and this list is growing. The purpose of Heat Shock Proteins and the Cardiovascular System is to give an overview of our current understanding of the heat shock proteins in the cardiovascular system, and to summarize the approaches to the study of heat shock proteins in the heart. This volume assembles results from a number of different cardiovascular fields, and provides a comprehensive review of heat shock proteins in the cardiovascular system.