CLINICAL TOXICOLOGIC EMERGENCIES

When a poisoned patient begins to deteriorate, memorized facts are not enough. You need a clinical framework that turns uncertainty into decisive action.

Clinical Toxicologic Emergencies is a comprehensive, board-focused guide designed to help emergency medicine residents, medical students, fellows, and advanced practice clinicians understand the mechanisms of poisoning, recognize critical patterns, and make sound management decisions under pressure.

Many toxicology references are either too extensive for efficient board preparation or too condensed to develop genuine clinical reasoning. This book bridges that gap by organizing complex material into a clear mechanism-to-diagnosis-to-management progression.

Rather than asking you to memorize disconnected antidotes and drug effects, it shows you how toxicokinetics, toxicodynamics, physical findings, laboratory abnormalities, ECG changes, and toxidromes work together at the bedside.

Inside, you will learn how to:

• Recognize major toxidromes and distinguish clinically similar presentations
• Interpret anion gaps, osmol gaps, acid-base disturbances, drug levels, and toxicologic ECG findings
• Select appropriate gastrointestinal decontamination and enhanced elimination strategies
• Manage analgesic, cardiovascular drug, psychotropic drug, toxic alcohol, heavy-metal, pesticide, and industrial chemical poisoning
• Respond to synthetic opioids, novel psychoactive substances, envenomation, poisonous plants, mushrooms, and foodborne toxins
• Apply antidote protocols, EXTRIP dialysis criteria, high-dose insulin therapy, lipid emulsion, modified ACLS, and ECMO principles
• Adapt toxicologic care for pediatric, pregnant, geriatric, and substance-use populations
• Determine appropriate observation periods, admission levels, discharge precautions, and Poison Control consultation points