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This issue will focus on treatments for Chronic Rhinosinusitis. Dr. Wyste Fokkens guest edits topics such as: Inflammatory mechanisms in chronic rhinosinusitis with or without nasal polyposis; European versus Asian Chronic rhinosinusitis; What did it teach us and what do we want to know; Epithelium, cilia and mucus, their importance in chronic rhinosinusitis Noam Cohen Noam; Aspirin intolerance - does desensitization alter the course of the disease; Anti-inflammatory effects of macrolides - applications in CRS; and, more.