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Changing Disciplines was intended to be a manifesto for a new medical creed that promoted clinical science as a field rather than a laboratory study, brought social science into the explanation of disease and returned the "whole patient" to the center of medical practice. In 1942, the author, John Alfred Ryle, resigned his chair at Cambridge to become the new director of a new Institute of Social Medicine established at the University of Oxford. In doing so he sacrificed on of the most senior academic positions in British medicine to embark on an educational adventure. His goal was to re-create medicine as a humanistic science, governed by what he called "social conscience as well as scientific intent."