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This text focuses on the interface between the conservation of plant genetic resources and their utilization. Only through utilization can the potential value of conserved genetic resources be realized. However, as this book shows, much conserved germplan has to be subjected to long-term pre-breeding and genetic enhancement before it can be used in plant breeding programmes. The authors explore the rationale and approaches for such pre-breeding efforts as the basis for broadening the gentic bases of crop production. Examples from a range of major food crops are presented and issues analyzed by authorities from around the world.