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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Breast cancer chemotherapy refers to the use of cytotoxic drugs (chemotherapy) in the treatment of breast cancer. There are three major types of chemotherapy. Neoadjuvant chemotherapy given before surgery to shrink the size of a tumor. Adjuvant chemotherapy given after surgery to reduce the risk of recurrence. Palliative chemotherapy used to control (but not cure) the cancer in settings in which the cancer has spread beyond the breast and localized lymph nodes.