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This volume contains the proceedings of the 12th International Symposium on Bioluminescence (BL) and Chemiluminescence (CL). It presents information on developments in BL and CL from scientists around the world. Light-emitting reactions are now a vital component of many key technologies in research and in routine analytical laboratories -replacing radionuclides in many situations. This text offers a compilation of the latest developments from key experts and leading-edge researchers in this area.