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This book constitutes the refereed proceedings of the 6th International Conference on Intelligent Computing, ICIC 2010, held in Changsha, China, in August 2010.The 85 revised full papers presented were carefully reviewed and selected from a numerous submissions. The papers of this volume are organized in topical sections on Biological and Quantum Computing, Intelligent Computing in Bioinformatics, Intelligent Computing in Neuroinformatics and Cheminformatics, Intelligent Computing in Computational Biology and Drug Design, Computational Genomics and Proteomics, Intelligent Computing in Signal Processing, Intelligent Computing in Pattern Recognition, Intelligent Computing in Image Processing, Intelligent Computing in Communication and Computer Networks, Intelligent Computing in Robotics, Intelligent Computing in Computer Vision, Intelligent Computing in Brain Imaging and Bio-medical Engineering, Intelligent Agent and Web Applications, Intelligent Sensor Networks, Intelligent Fault Diagnosis & Financial Engineering, Intelligent Control and Automation, Intelligent Data Fusion and Security, Intelligent Prediction & Time Series Analysis, Natural Language Processing and Expert Systems.